NSHD DNA Repository
Around 2,900 study members have given consent
for DNA to be extracted from blood and/or buccal samples and LHA
was given ethical approval in 2007 to use these samples for genetic
studies of lifelong health and ageing. Genetic studies help us to
elucidate biological mechanisms of ageing and understand why people
with similar life experiences age differently.
The NSHD DNA Repository supports high calibre
studies of human health and disease that make the best use of the
genetic resource in conjunction with the existing life course data.
Dr Andrew Wong coordinates the genetic
research of the NSHD and is responsible for the safe storage and
efficient use of the samples, which are managed by Source
BioScience.
Researchers wishing to use the NSHD DNA samples should apply to
Dr Andrew Wong briefly outlining their project and
requesting a data application form.
Ongoing genetics projects using the DNA
Repository include collaborations with:
- UCL on genetic studies of heart disease and
immunity
- Edinburgh University on the genetic basis of
cognitive changes from childhood to middle age
- MRC Epidemiology Unit on obesity-related
genetic variants
- Cambridge University on the genetics of
mental health and illness
- Institute of Ageing, Newcastle University, on
telomere length and ageing
- HALCyon cohorts on the genetics of
ageing
- University of Exeter on the genetics of
menopause and ageing